WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX55843 XPA antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX55843 XPA antibody. Dilution : 1:1000 Loading : 25microg per lane
XPA antibody - KO/KD Validated
GTX55843
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetXPA
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Overview
- SupplierGeneTex
- Product NameXPA antibody - KO/KD Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7507
- Target nameXPA
- Target descriptionXPA, DNA damage recognition and repair factor
- Target synonymsDNA repair protein complementing XP-A cells; xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPAC
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203