XPC antibody [C2C3], C-term

GeneTex

XPC antibody [C2C3], C-term

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.16 mg/ml

Unconjugated

XPC

XPC complex subunit, DNA damage recognition and repair factor

RAD4, XP3, XPCC, p125, DNA repair protein complementing XP-C cells, mutant xeroderma pigmentosum group C, xeroderma pigmentosum, complementation group C

Rabbit

IgG

DNA repair protein complementing XP-C cells

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203