XPC antibody

GeneTex

XPC antibody

9

Human XPC

For WB: Load 40ug cell lysate/lane. Use at a dilution of 1:500-1:1000. Optimal dilutions/concentratons should be determined by the researcher.

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

Liquid

XPC

XPC complex subunit, DNA damage recognition and repair factor

DNA repair protein complementing XP-C cells; mutant xeroderma pigmentosum group C; p125; RAD4; xeroderma pigmentosum, complementation group C; XP3; XPCC

Rabbit

IgG

DNA repair protein complementing XP-C cells

The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203