6BIO

AdipoGen Life Sciences

6BIO

10

667463-62-9

Research Use Only

>99%

Warning

C16H10BrN3O2

356.2

Chemical. CAS: 667463-62-9. Formula: C16H10BrN3O2. MW: 356.2. Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Anticancer compound. Potent antiproliferative agent. Suppresses metastasis. Apoptosis inducer. Sustains pluripotency and self-renewal of human and mouse embryonic stem cells (ESCs) by activation of the Wnt signaling pathway. Anti-leishmanial (IC50 = 0.150microM). Proto-oncogene tyrosine-protein kinase receptor RET inhibitor (IC50=0.51microM). Inhibits HIV-1 transcription and protects against Tat induced neurotoxicity. - Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Anticancer compound. Potent antiproliferative agent. Suppresses metastasis. Apoptosis inducer. Sustains pluripotency and self-renewal of human and mouse embryonic stem cells (ESCs) by activation of the Wnt signaling pathway. Anti-leishmanial (IC50 = 0.150microM). Proto-oncogene tyrosine-protein kinase receptor RET inhibitor (IC50=0.51microM). Inhibits HIV-1 transcription and protects against Tat induced neurotoxicity.

O\N=C1\C(\NC2=CC=CC=C\12)=C1\C(=O)NC2=C1C=CC(Br)=C2

-20°C,2°C to 8°C

51202000