
Chemical Structure
K-252a [99533-80-9]

AG-CN2-0019
Overview
- SupplierAdipoGen Life Sciences
- Product NameK-252a
- Delivery Days Customer10
- CAS Number99533-80-9
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC27H21N3O5
- Molecular Weight467.5
- Scientific DescriptionAntibiotic [1]. PKC, PKA and PKG inhibitor [1, 2, 4]. Shows neurotropic activity by inducing neurite outgrowth [3, 8, 11,16]. Highly potent cell permeable CaM kinase [6] and phosphorylase inhibitor [5]. Tyrosine protein kinase inhibitor of the TRK family [7]. Antiproliferative [9, 10, 13, 15]. Apoptosis inducer [12, 16]. Cell cycle arrest inducer [12]. Potential drug for psoriasis treatment [14]. - Chemical. CAS: 99533-80-9. Formula: C27H21N3O5. MW: 467.5. Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK family. Antiproliferative. Apoptosis inducer. Cell cycle arrest inducer. Potential drug for psoriasis treatment.
- SMILES[H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200