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Chemical Structure
Chemical Structure
Chemical Structure

K-252a [99533-80-9]

Research Use Only
AG-CN2-0019
AdipoGen Life Sciences
CAS Number99533-80-9
Product group Chemicals
Estimated Purity>98%
Molecular Weight467.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    K-252a
  • Delivery Days Customer
    10
  • CAS Number
    99533-80-9
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C27H21N3O5
  • Molecular Weight
    467.5
  • Scientific Description
    Antibiotic [1]. PKC, PKA and PKG inhibitor [1, 2, 4]. Shows neurotropic activity by inducing neurite outgrowth [3, 8, 11,16]. Highly potent cell permeable CaM kinase [6] and phosphorylase inhibitor [5]. Tyrosine protein kinase inhibitor of the TRK family [7]. Antiproliferative [9, 10, 13, 15]. Apoptosis inducer [12, 16]. Cell cycle arrest inducer [12]. Potential drug for psoriasis treatment [14]. - Chemical. CAS: 99533-80-9. Formula: C27H21N3O5. MW: 467.5. Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK family. Antiproliferative. Apoptosis inducer. Cell cycle arrest inducer. Potential drug for psoriasis treatment.
  • SMILES
    [H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200