KBU2046

AdipoGen Life Sciences

KBU2046

10

1143863-69-7

Research Use Only

>98%

C15H11FO2

242.2

Chemical. CAS: 1143863-69-7. Formula: C15H11FO2. MW: 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity. - Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.

O=C1C(C2=CC=C(F)C=C2)COC3=CC=CC=C31

-20°C,2°C to 8°C

12352200