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ProductsBack/Actin antibody [AC-40] (Cy3)

Actin antibody [AC-40] (Cy3)

Research Use Only
GTX11004
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityBovine, Canine, Chicken, Fish, Guinea Pig, Goat, Hamster, Human, Molluscs, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep, Xenopus
TargetACTA1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Actin antibody [AC-40] (Cy3)
  • Delivery Days Customer
    9
  • Application Supplier Note
    ICC/IF: 1:75. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AC-40
  • Conjugate
    Cy3
  • Formulation
    Liquid
  • Gene ID58
  • Target name
    ACTA1
  • Target description
    actin alpha 1, skeletal muscle
  • Target synonyms
    ACTA; actin, alpha skeletal muscle; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP68133
  • Protein Name
    Actin, alpha skeletal muscle
  • Scientific Description
    The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Although actin is one of the most conserved eukaryotic proteins, it is expressed in mammals and birds as at least six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of them represent the differentiation markers of muscle tissues and two are found in practically all cells.
  • Reactivity
    Bovine, Canine, Chicken, Fish, Guinea Pig, Goat, Hamster, Human, Molluscs, Mouse, Porcine, Rabbit, Reptile, Rat, Sheep, Xenopus
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Mcl-1 Differentially Regulates Autophagy in Response to Changes in Energy Status and Mitochondrial Damage. Moyzis AG et al., 2022 Apr 27, Cells
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  • Silicified collagen scaffold induces semaphorin 3A secretion by sensory nerves to improve in-situ bone regeneration. Ma YX et al., 2022 Mar, Bioact Mater
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  • Activity of Lymphostatin, A Lymphocyte Inhibitory Virulence Factor of Pathogenic Escherichia coli, is Dependent on a Cysteine Protease Motif. Bease AG et al., 2021 Sep 17, J Mol Biol
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  • MicroRNA-301a-3p promotes triple-negative breast cancer progression through downregulating MEOX2. Liu H et al., 2021 Sep, Exp Ther Med
    Read more
  • Silencing DNA Polymerase beta Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer. Wang HC et al., 2021 Feb 27, Int J Mol Sci
    Read more
  • Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise. Moyzis AG et al., 2020 Sep, J Mol Cell Cardiol
    Read more
  • Arginine methylation of APE1 promotes its mitochondrial translocation to protect cells from oxidative damage. Zhang Y et al., 2020 Oct, Free Radic Biol Med
    Read more
  • Astrocytes influence medulloblastoma phenotypes and CD133 surface expression. Gronseth E et al., 2020, PLoS One
    Read more
  • Levetiracetam Protects Against Cognitive Impairment of Subthreshold Convulsant Discharge Model Rats by Activating Protein Kinase C (PKC)-Growth-Associated Protein 43 (GAP-43)-Calmodulin-Dependent Protein Kinase (CaMK) Signal Transduction Pathway. Wang MJ et al., 2019 Jun 22, Med Sci Monit
    Read more
  • Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit. Kuo CC et al., 2019, Theranostics
    Read more