WB analysis of truncated Trx-AR recombinant protein (1) using GTX83145 Androgen Receptor antibody [1A9D12].
WB analysis of truncated Trx-AR recombinant protein (1) using GTX83145 Androgen Receptor antibody [1A9D12].
Androgen Receptor antibody [1A9D12]
GTX83145
Overview
- SupplierGeneTex
- Product NameAndrogen Receptor antibody [1A9D12]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1A9D12
- ConjugateUnconjugated
- Gene ID367
- Target nameAR
- Target descriptionandrogen receptor
- Target synonymsAIS; androgen receptor; AR8; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; TFM
- HostMouse
- IsotypeIgG1
- Protein IDP10275
- Protein NameAndrogen receptor
- Scientific DescriptionThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203