Anti-Complement C3 [1H8]

Absolute Antibody

Anti-Complement C3 [1H8]

9

To show that a monoclonal antibody directed against the merozoite and human polyclonal IgG from merozoite vaccine recipients enhanced RBC invasion in a complement-dependent manner, immunofluorescence was performed on merozoites with RBC using the mouse version of this antibody (Biryukov et al, 2016; pmid:27333049). Flow cytometry was performed on intact and lysed PNH erythrocytes using the mouse version of this antibody to analyze the deposition of C3 (Lindorfer et al, 2010; pmid:20068220). While studying the role of the complement system in childhood malaria, immunoprecipitation was performed on erythrocytes using the mouse version of this antibody. Furthermore, a western blot was performed on erythrocytes using this antibody (Pawluczkowycz et al, 2007; pmid:17911641). To examine the ability of several commercially available phycoerythrin (PE)-labeled anti-Mouse IgG antibodies to bind to B cells opsonized in milieu which allow or preclude complement activation, flow cytometry was performed on Raji cells, Z138C cells or CLL patient B cells using the mouse version of this antibody. Furthermore, Raji cells, Z138C cells or CLL patient B cells were stained for immunofluorescence using this antibody (Beum et al, 2004; pmid:15604014).

Flow Cytometry, ImmunoFluorescence, Western Blot

Research Use Only

Monoclonal

1H8

C3

complement C3

AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a anaphylatoxin, acylation-stimulating protein cleavage product, complement component 3, complement component C3a, complement component C3b, epididymis secretory sperm binding protein Li 62p, prepro-C3

Mouse

IgG2a

Complement C3

Human

-20°C,2°C to 8°C

12352203