Anti-Hu CD279 Purified Low Endotoxin

EXBIO

Anti-Hu CD279 Purified Low Endotoxin

7

The mouse monoclonal antibody EH12.2H7 recognizes an extracellular epitope of CD279 / PD-1 (programmed cell death 1), a 55 kDa type I transmembrane protein expressed above all during T cell development, on activated T cells, activated B cells, and activat

Functional application: Blocking. Flow cytometry: Recommended dilution: 1-4 microg/ml

Functional Assay, Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

EH12.2H7

1 mg/ml

IgG1

CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its ligands CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.

Human, Primate

2°C to 8°C

12352203