Anti-TGFalpha [tAb2]

Absolute Antibody

Anti-TGFalpha [tAb2]

9

tAb2 binds the N-terminal sequence of transforming growth factor alpha, VVSHFND (with residues 4 to 7 being the minimal binding epitope).

Human transforming growth factora (TGFa) consists of 50 amino acid residues with three disulphide bridges. It belongs to the family of epidermal growth factor related peptides and binds to EGFreceptor. It is involved in cell proliferation in healthy cells and is found in various cancer cells. Transfection of Fibroblasts with the TGFa gene induces tumor formation.

Dot Blot, ELISA, Other Application

Research Use Only

Monoclonal

tAb2

TGFA

transforming growth factor alpha

protransforming growth factor alpha; TFGA; TGF-alpha

Rabbit

IgG

Protransforming growth factor alpha

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203