More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/beta Catenin antibody

beta Catenin antibody

GTX101254
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCTNNB1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    beta Catenin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.01 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1499
  • Target name
    CTNNB1
  • Target description
    catenin beta 1
  • Target synonyms
    CTNNB, EVR7, MRD19, NEDSDV, armadillo, catenin beta-1, catenin (cadherin-associated protein), beta 1, 88kDa
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35222
  • Protein Name
    Catenin beta-1
  • Scientific Description
    Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Zuo Z, Ji S, He L, et al. LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3β/β-catenin pathway. Cell Biol Int. 2020,44(11):2284-2292. doi: 10.1002/cbin.11436
    Read this paper
  • Liu J, Cao L, Zhao N, et al. miR‑338‑3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and β‑catenin signaling pathways. Mol Med Rep. 2019,20(1):33-40. doi: 10.3892/mmr.2019.10215
    Read this paper
  • Wu ZH, Tao ZH, Zhang J, et al. MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer. Tumour Biol. 2016,37(6):7245-54. doi: 10.1007/s13277-015-4604-7
    Read this paper
  • Mohapatra S, Chakraborty T, Shimizu S, et al. Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major). Comp Biochem Physiol A Mol Integr Physiol. 2015,189:1-10. doi: 10.1016/j.cbpa.2015.07.003
    Read this paper
  • Król M, Mucha J, Majchrzak K, et al. Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. PLoS One. 2014,9(1):e83995. doi: 10.1371/journal.pone.0083995
    Read this paper
  • Hong GM, Bain LJ. Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway. Toxicol Sci. 2012,129(1):146-56. doi: 10.1093/toxsci/kfs186
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Product group Antibodies
Biomatik
Ctnnb1 Polyclonal AntibodyCAC07113
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
TargetCTNNB1
  • SizePrice
Product group Antibodies
Assay Genie
[KO Validated] beta-Catenin Monoclonal AntibodyCAB19657
TargetCTNNB1
  • SizePrice
Image provided by One World Lab validation program. U138 cells probed with Rabbit Anti-Beta catenin Polyclonal Antibody (bs-1165R) at 1:50 for 60 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Alexa Fluor 488 Conjugated secondary antibody.
Product group Antibodies
References
Bioss
Beta catenin Polyclonal AntibodyBS-1165R
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetCTNNB1
  • SizePrice
Anti-beta Catenin Antibody
Product group Antibodies
Antibodies.com
Anti-beta Catenin AntibodyA121145
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA
  • SizePrice
Figure 1. Western blot analysis of CTNNB1 using anti-CTNNB1 antibody (A00004). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human MCF-7 whole cell lysates, Lane 2: human A431 whole cell lysates, Lane 3: human RT4 whole cell lysates, Lane 4: human T47D whole cell lysates, Lane 5: human A549 whole cell lysates, Lane 6: human PC-3 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CTNNB1 antigen affinity purified polyclonal antibody (Catalog # A00004) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CTNNB1 at approximately 95 kDa. The expected band size for CTNNB1 is at 95 kDa.
Product group Antibodies
Boster Bio
Anti-beta Catenin/CTNNB1 Antibody Picoband(r)A00004-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetCTNNB1
  • SizePrice
Product group Antibodies
RayBiotech
Anti-CTNNB1 Antibody144-11512
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetCTNNB1
  • SizePrice
Immunohistochemical staining of human endometrium shows strong membranous immunoreactivity in glandular epithelium.
Product group Antibodies
Atlas Antibodies
Anti-CTNNB1 AntibodyAMAB91209
ApplicationsWestern Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
ReactivityHuman
TargetCTNNB1
  • SizePrice
Product group Antibodies
Absolute Antibody
Anti-beta catenin [15B8]Ab01655-1.1
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, Other Application
TargetCTNNB1
  • SizePrice
Product group Antibodies
Everest Biotech
Goat anti-CTNNB1 / catenin beta-1EB12542
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA
TargetCTNNB1
  • SizePrice
ICC/IF analysis of PFA-fixed C6 cells using GTX00948 beta Catenin antibody [GT1186]. Orange : Primary antibody Blue : DAPI Dilution : 1:100
Product group Antibodies
GeneTex
beta Catenin antibody [GT1186]GTX00948
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetCTNNB1
  • SizePrice