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beta Catenin antibody

GTX101254
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetCTNNB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    beta Catenin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.01 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1499
  • Target name
    CTNNB1
  • Target description
    catenin beta 1
  • Target synonyms
    armadillo; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; EVR7; MRD19; NEDSDV
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35222
  • Protein Name
    Catenin beta-1
  • Scientific Description
    Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol Int
    Read more
  • miR-338-3p inhibits A549 lung cancer cell proliferation and invasion by targeting AKT and beta-catenin signaling pathways. Liu J et al., 2019 Jul, Mol Med Rep
    Read more
  • MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer. Wu ZH et al., 2016 Jun, Tumour Biol
    Read more
  • Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major). Mohapatra S et al., 2015 Nov, Comp Biochem Physiol A Mol Integr Physiol
    Read more
  • Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. Krol M et al., 2014, PLoS One
    Read more
  • Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the beta-catenin signaling pathway. Hong GM et al., 2012 Sep, Toxicol Sci
    Read more

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