ICC/IF analysis of PFA-fixed C6 cells using GTX00948 beta Catenin antibody [GT1186]. Orange : Primary antibody Blue : DAPI Dilution : 1:100
![IHC-P analysis of Rat pancreas tissue section using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_20200327_IHC-P_15_w_23053121_745.webp "IHC-P analysis of Rat pancreas tissue section using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:100")
![IHC-P analysis of Human colon carcinoma tissue section using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_20200327_IHC-P_16_w_23053121_984.webp "IHC-P analysis of Human colon carcinoma tissue section using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:100")
![WB analysis of HeLa whole cell lysate using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_20200327_WB_1_w_23053121_214.webp "WB analysis of HeLa whole cell lysate using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000")
![WB analysis of Mouse brain tissue lysate using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_20200327_WB_2_w_23053121_898.webp "WB analysis of Mouse brain tissue lysate using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000")
![WB analysis of wild-type (WT) and beta Catenin knockout (KO) 293T cell extracts using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000 Laoding : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_20200327_WB_3_w_23053121_371.webp "WB analysis of wild-type (WT) and beta Catenin knockout (KO) 293T cell extracts using GTX00948 beta Catenin antibody [GT1186]. Dilution : 1:1000 Laoding : 25microg")
![Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody [GT1186] (GTX00948) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX00948/GTX00948_4000000136_20200313_WB_w_23053121_906.webp "Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with beta Catenin antibody [GT1186] (GTX00948) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
ICC/IF analysis of PFA-fixed C6 cells using GTX00948 beta Catenin antibody [GT1186]. Orange : Primary antibody Blue : DAPI Dilution : 1:100
beta Catenin antibody [GT1186] - Recombinant antibody, KO/KD Validated
GTX00948
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCTNNB1
Overview
- SupplierGeneTex
- Product Namebeta Catenin antibody [GT1186] - Recombinant antibody, KO/KD Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1186
- ConjugateUnconjugated
- Gene ID1499
- Target nameCTNNB1
- Target descriptioncatenin beta 1
- Target synonymsarmadillo; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; EVR7; MRD19; NEDSDV
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203