Bio-Connect

beta Tubulin 3/ Tuj1 antibody [GT11710]

GTX631836
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityFish, Human, Mouse, Rat
TargetTUBB3
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Overview

  • Supplier
    GeneTex
  • Product Name
    beta Tubulin 3/ Tuj1 antibody [GT11710]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT11710
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10381
  • Target name
    TUBB3
  • Target description
    tubulin beta 3 class III
  • Target synonyms
    CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta-3 chain, class III beta-tubulin, tubulin beta-4 chain, tubulin beta-III, tubulin, beta 3
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ13509
  • Protein Name
    Tubulin beta-3 chain
  • Scientific Description
    This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq]
  • Reactivity
    Fish, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Hosoya M, Kitama T, Shimanuki MN, et al. Distribution of macrophages in the developing cochlea of the common marmoset, a primate model animal. Front Immunol. 2023,14:1229414. doi: 10.3389/fimmu.2023.1229414
    Read this paper
  • Jin C, Wu Y, Zhang H, et al. Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes. Bioeng Transl Med. 2023,8(2):e10448. doi: 10.1002/btm2.10448
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  • Ma PW, Wang WL, Chen JW, et al. Treatment with the Ferroptosis Inhibitor Ferrostatin-1 Attenuates Noise-Induced Hearing Loss by Suppressing Ferroptosis and Apoptosis. Oxid Med Cell Longev. 2022,2022:3373828. doi: 10.1155/2022/3373828
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  • Hosoya M, Fujioka M, Okahara J, et al. Early development of the cochlea of the common marmoset, a non-human primate model. Neural Dev. 2022,17(1):6. doi: 10.1186/s13064-022-00162-8
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  • Kim JY, Mo H, Kim J, et al. Mitigating Effect of Estrogen in Alzheimer's Disease-Mimicking Cerebral Organoid. Front Neurosci. 2022,16:816174. doi: 10.3389/fnins.2022.816174
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  • Yang Y, Lu W, Ning M, et al. A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1. Commun Biol. 2022,5(1):309. doi: 10.1038/s42003-022-03263-6
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  • Chen JW, Ma PW, Yuan H, et al. mito-TEMPO Attenuates Oxidative Stress and Mitochondrial Dysfunction in Noise-Induced Hearing Loss via Maintaining TFAM-mtDNA Interaction and Mitochondrial Biogenesis. Front Cell Neurosci. 2022,16:803718. doi: 10.3389/fncel.2022.803718
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  • Vajhøj C, Schmid B, Alik A, et al. Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation. PLoS One. 2021,16(12):e0261536. doi: 10.1371/journal.pone.0261536
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  • Rey F, Pandini C, Messa L, et al. α-Synuclein antisense transcript SNCA-AS1 regulates synapses- and aging-related genes suggesting its implication in Parkinson's disease. Aging Cell. 2021,20(12):e13504. doi: 10.1111/acel.13504
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