The data was published in the journal Front Neurosci in 2018.PMID: 29515358
The data was published in the journal Front Neurosci in 2018.PMID: 29515358
beta Tubulin 3/ Tuj1 antibody
GTX85469
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTUBB3
Overview
- SupplierGeneTex
- Product Namebeta Tubulin 3/ Tuj1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:10000-1:20000. IHC: 1:2000-1:5000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration100 ug/ml
- ConjugateUnconjugated
- Gene ID10381
- Target nameTUBB3
- Target descriptiontubulin beta 3 class III
- Target synonymsCDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta-3 chain, class III beta-tubulin, tubulin beta-4 chain, tubulin beta-III, tubulin, beta 3
- HostChicken
- IsotypeIgY
- Protein IDQ13509
- Protein NameTubulin beta-3 chain
- Scientific DescriptionThis gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- O'Brien BS, Mokry RL, Schumacher ML, et al. Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus. J Virol. 2023,97(10):e0069623. doi: 10.1128/jvi.00696-23Read this paper
- Zhang X, Zhou K, Tian K, et al. VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway. Cells. 2022,11(23). doi: 10.3390/cells11233746Read this paper
- Wang T, Tian X, Kim HB, et al. Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules. Nat Commun. 2022,13(1):5584. doi: 10.1038/s41467-022-33079-1Read this paper
- Vahsen BF, Gray E, Candalija A, et al. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons. Sci Rep. 2022,12(1):12606. doi: 10.1038/s41598-022-16896-8Read this paper
- O'Brien BS, Mokry RL, Schumacher ML, et al. Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus. iScience. 2022,25(4):104098. doi: 10.1016/j.isci.2022.104098Read this paper
- Kumar R, Huang YT, Chen CC, et al. Astrocytic Regulation of Synchronous Bursting in Cortical Cultures: From Local to Global. Cereb Cortex Commun. 2020,1(1):tgaa053. doi: 10.1093/texcom/tgaa053Read this paper
- Roy S, Sen CK, Ghatak S, et al. Neurogenic tissue nanotransfection in the management of cutaneous diabetic polyneuropathy. Nanomedicine. 2020,28:102220. doi: 10.1016/j.nano.2020.102220Read this paper
- Sison SL, O'Brien BS, Johnson AJ, et al. Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and Organoids. J Virol. 2019,93(17). doi: 10.1128/JVI.00954-19Read this paper
- Hauser M, Yan R, Li W, et al. The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage. Cell Rep. 2018,24(6):1512-1522. doi: 10.1016/j.celrep.2018.07.005Read this paper
- Santarriaga S, Haver HN, Kanack AJ, et al. SRCP1 Conveys Resistance to Polyglutamine Aggregation. Mol Cell. 2018,71(2):216-228.e7. doi: 10.1016/j.molcel.2018.07.008Read this paper
Datasheet
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