BUB1 antibody
GTX107497
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetBUB1
Overview
- SupplierGeneTex
- Product NameBUB1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.63 mg/ml
- ConjugateUnconjugated
- Gene ID699
- Target nameBUB1
- Target descriptionBUB1 mitotic checkpoint serine/threonine kinase
- Target synonymsBUB1A, BUB1L, MCPH30, hBUB1, mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1 budding uninhibited by benzimidazoles 1 homolog, budding uninhibited by benzimidazoles 1 homolog, mitotic spindle checkpoint kinase, putative serine/threonine-protein kinase
- HostRabbit
- IsotypeIgG
- Protein IDO43683
- Protein NameMitotic checkpoint serine/threonine-protein kinase BUB1
- Scientific DescriptionThis gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Rodriguez-Rodriguez JA, Lewis C, McKinley KL, et al. Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion. Curr Biol. 2018,28(21):3422-3429.e5. doi: 10.1016/j.cub.2018.10.006Read this paper
- Zhou H, Wang T, Zheng T, et al. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016,7:10151. doi: 10.1038/ncomms10151Read this paper




