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Western blot analysis of CaMK2 alpha/delta expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of CaMK2 alpha/delta expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of CaMK2 alpha/delta expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

CaMK2 alpha/delta antibody

GTX52377
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAMK2A
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Overview

  • Supplier
    GeneTex
  • Product Name
    CaMK2 alpha/delta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID815
  • Target name
    CAMK2A
  • Target description
    calcium/calmodulin dependent protein kinase II alpha
  • Target synonyms
    CAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63, calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II alpha subunit, CaM-kinase II alpha chain, CaMK-II alpha subunit, caM kinase II subunit alpha, caMK-II subunit alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cai R, Wang P, Zhao X, et al. Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance. Cancer Sci. 2022,113(10):3593-3607. doi: 10.1111/cas.15487
    Read this paper
  • Dai W, Choubey M, Patel S, et al. Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance. Mol Metab. 2021,53:101300. doi: 10.1016/j.molmet.2021.101300
    Read this paper