
Western blot analysis of CaMK2 alpha/delta expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
CaMK2 alpha/delta antibody
GTX52377
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAMK2A
Overview
- SupplierGeneTex
- Product NameCaMK2 alpha/delta antibody
- Delivery Days Customer9
- Application Supplier NoteWB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID815
- Target nameCAMK2A
- Target descriptioncalcium/calmodulin dependent protein kinase II alpha
- Target synonymsCAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63, calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II alpha subunit, CaM-kinase II alpha chain, CaMK-II alpha subunit, caM kinase II subunit alpha, caMK-II subunit alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cai R, Wang P, Zhao X, et al. Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance. Cancer Sci. 2022,113(10):3593-3607. doi: 10.1111/cas.15487Read this paper
- Dai W, Choubey M, Patel S, et al. Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance. Mol Metab. 2021,53:101300. doi: 10.1016/j.molmet.2021.101300Read this paper





![Untreated (–) and treated (+) mouse brain extract (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with CaMKII alpha (phospho Thr286) antibody [HL3570] (GTX641517) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641517/GTX641517_45439_20241227_WB_M_brain_treatment_CIP_24123021_303.webp)

