
ICC/IF analysis of PFA fixed U251 cells using GTX88413 CaMKII alpha antibody, Internal. Green : Primary antibody Blue : DAPI Negative control : Unimmunized goat IgG Permeabilization : 0.15% Triton Dilution : 10microg/ml
CaMKII alpha antibody, Internal
GTX88413
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAMK2A
Overview
- SupplierGeneTex
- Product NameCaMKII alpha antibody, Internal
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to recognize both reported isoforms (NP_057065.2; NP_741960.1).
- Application Supplier NoteWB: 0.03-0.3microg/ml. ICC/IF: 10microg/ml. IHC-P: 3.75microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID815
- Target nameCAMK2A
- Target descriptioncalcium/calmodulin dependent protein kinase II alpha
- Target synonymscalcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II alpha subunit; caM kinase II subunit alpha; CAMKA; CaMK-II alpha subunit; caMK-II subunit alpha; CaMKIIalpha; CaMKIINalpha; CaM-kinase II alpha chain; MRD53; MRT63
- HostGoat
- IsotypeIgG
- Protein IDQ9UQM7
- Protein NameCalcium/calmodulin-dependent protein kinase type II subunit alpha
- Scientific DescriptionThe product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203