Cardiac Troponin I antibody [415]
GTX14495
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
Product group Antibodies
ReactivityHuman
TargetTNNI3
Overview
- SupplierGeneTex
- Product NameCardiac Troponin I antibody [415]
- Delivery Days Customer9
- Antibody SpecificityNo cross-reactivity with skeletal muscle TnI.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID415
- ConjugateUnconjugated
- Gene ID7137
- Target nameTNNI3
- Target descriptiontroponin I3, cardiac type
- Target synonymscardiomyopathy, dilated 2A (autosomal recessive); CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1; troponin I type 3 (cardiac); troponin I, cardiac muscle
- HostMouse
- IsotypeIgG1
- Scientific DescriptionTroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203