WB analysis of COS7 cells treated with etoposide 25uM 1h using GTX86884 Cathepsin D (cleaved Gly65) antibody.
Cathepsin D (cleaved Gly65) antibody
GTX86884
Overview
- SupplierGeneTex
- Product NameCathepsin D (cleaved Gly65) antibody
- Delivery Days Customer9
- Antibody SpecificityCathepsin D (cleaved Gly65) antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Gly65.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1509
- Target nameCTSD
- Target descriptioncathepsin D
- Target synonymscathepsin D; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease. [provided by RefSeq, Nov 2015]
- ReactivityHuman, Monkey
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203