Cathepsin D (cleaved Leu169) antibody

GeneTex

Cathepsin D (cleaved Leu169) antibody

9

Cathepsin D (cleaved Leu169) antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Leu169.

Western Blot

Research Use Only

Polyclonal

Unconjugated

CTSD

cathepsin D

cathepsin D; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease

Rabbit

IgG

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimers disease. [provided by RefSeq, Nov 2015]

Human

2°C to 8°C,-20°C or -80°C

12352203