CD27 antibody [LT27] (PE-Cy7)

GeneTex

CD27 antibody [LT27] (PE-Cy7)

9

FACS: 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry

Research Use Only

Monoclonal

LT27

Double Conjugated

CD27

CD27 molecule

S152, S152. LPFS2, T14, TNFRSF7, Tp55, CD27 antigen, CD27L receptor, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily, member 7

Mouse

IgG2a

CD27 antigen

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

2°C to 8°C

12352203