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CD63 antibody [MEM-259] (APC)

Name: CD63 antibody [MEM-259] (APC)
SKU: GTX79963_G10
Availability: BackOrder

GTX79963

ApplicationsFlow Cytometry

Product group Antibodies

ReactivityHuman

TargetCD63

Overview

Supplier
GeneTex
Product Name
CD63 antibody [MEM-259] (APC)
Delivery Days Customer
9
Application Supplier Note
FACS: 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
MEM-259
Conjugate
APC (Allophycocyanin)
Gene ID967
Target name
CD63
Target description
CD63 molecule
Target synonyms
AD1, HOP-26, ME491, MLA1, OMA81H, Pltgp40, TSPAN30, CD63 antigen, AD1 antigen, CD63 antigen (melanoma 1 antigen), granulophysin, limp1, melanoma-associated antigen ME491, melanoma-associated antigen MLA1, ocular melanoma-associated antigen, tetraspanin-30, tspan-30
Host
Mouse
Isotype
IgG1
Protein IDP08962
Protein Name
CD63 antigen
Scientific Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Reactivity
Human
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Lanna A, Vaz B, D'Ambra C, et al. An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory. Nat Cell Biol. 2022,24(10):1461-1474. doi: 10.1038/s41556-022-00991-z
Read this paper
Zhang C, Chong X, Jiang F, et al. Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer. J Extracell Vesicles. 2022,11(4):e12209. doi: 10.1002/jev2.12209
Read this paper
Lenzini S, Debnath K, Joshi JC, et al. Cell-Matrix Interactions Regulate Functional Extracellular Vesicle Secretion from Mesenchymal Stromal Cells. ACS Nano. 2021,15(11):17439-17452. doi: 10.1021/acsnano.1c03231
Read this paper
Peng X, Li X, Yang S, et al. LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation. J Exp Clin Cancer Res. 2021,40(1):183. doi: 10.1186/s13046-021-01990-y
Read this paper
Peng X, Yang L, Ma Y, et al. IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells. Biochim Biophys Acta Mol Cell Res. 2021,1868(1):118857. doi: 10.1016/j.bbamcr.2020.118857
Read this paper
Yang L, Peng X, Li Y, et al. Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma. Mol Cancer. 2019,18(1):78. doi: 10.1186/s12943-019-0990-6
Read this paper
Raulf N, Lucarelli P, Thavaraj S, et al. Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers. Eur J Cancer. 2018,102:52-68. doi: 10.1016/j.ejca.2018.07.123
Read this paper
Jakhria T, Hellewell AL, Porter MY, et al. β2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes. J Biol Chem. 2014,289(52):35781-94. doi: 10.1074/jbc.M114.586222
Read this paper

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CD63 antibody [MEM-259] (APC)

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