CD63 antibody [MEM-259] (PerCP)
GTX79964
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetCD63
Overview
- SupplierGeneTex
- Product NameCD63 antibody [MEM-259] (PerCP)
- Delivery Days Customer9
- Application Supplier NoteFACS: 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-259
- ConjugatePerCP
- FormulationLiquid
- Gene ID967
- Target nameCD63
- Target descriptionCD63 molecule
- Target synonymsCD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30
- HostMouse
- IsotypeIgG1
- Protein IDP08962
- Protein NameCD63 antigen
- Scientific DescriptionThe protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer. Zhang C et al., 2022 Apr, J Extracell VesiclesRead more
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation. Peng X et al., 2021 Jun 4, J Exp Clin Cancer ResRead more
- IKKbeta activation promotes amphisome formation and extracellular vesicle secretion in tumor cells. Peng X et al., 2021 Jan, Biochim Biophys Acta Mol Cell ResRead more
- Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma. Yang L et al., 2019 Apr 3, Mol CancerRead more
- Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers. Raulf N et al., 2018 Oct, Eur J CancerRead more
- beta2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes. Jakhria T et al., 2014 Dec 26, J Biol ChemRead more