Western blot of rat neonatal brain lysate showing specific immunolabeling of the ~62k COBRA1 protein using COBRA1 (NELF-B) antibody [F7E4] (GTX82722).
Western blot of rat neonatal brain lysate showing specific immunolabeling of the ~62k COBRA1 protein using COBRA1 (NELF-B) antibody [F7E4] (GTX82722).
COBRA1 antibody [F7E4]
GTX82722
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNELFB
Overview
- SupplierGeneTex
- Product NameCOBRA1 antibody [F7E4]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDF7E4
- ConjugateUnconjugated
- Gene ID25920
- Target nameNELFB
- Target descriptionnegative elongation factor complex member B
- Target synonymsCOBRA1; cofactor of BRCA1; negative elongation factor B; negative elongation factor protein B; NELF-B
- HostMouse
- IsotypeIgG1
- Scientific DescriptionNELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. Menard M et al., 2018 May, PLoS BiolRead more