Western blot analysis of extracts from COLO205 cells using cofilin antibody (Lane 1 and 2) and cofilin (phospho-Ser3) antibody (GTX12866, Lane 3 and 4)
Western blot analysis of extracts from COLO205 cells using cofilin antibody (Lane 1 and 2) and cofilin (phospho-Ser3) antibody (GTX12866, Lane 3 and 4)
Cofilin 1 (phospho Ser3) antibody
GTX12866
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCFL1
Overview
- SupplierGeneTex
- Product NameCofilin 1 (phospho Ser3) antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1072
- Target nameCFL1
- Target descriptioncofilin 1
- Target synonymsCFL, HEL-S-15, cofilin, cofilin-1, 18 kDa phosphoprotein, cofilin 1 (non-muscle), epididymis secretory protein Li 15, p18
- HostRabbit
- IsotypeIgG
- Protein IDP23528
- Protein NameCofilin-1
- Scientific DescriptionThe protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Toyo-oka K, Wachi T, Hunt RF, et al. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014,34(36):12168-81. doi: 10.1523/JNEUROSCI.2513-13.2014Read this paper
Datasheet
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