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GTX112731 IHC-P Image
GTX112731 IHC-P Image
GTX112731 IHC-P Image

COL1A1 antibody [N1N2], N-term

Research Use Only
GTX112731
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    COL1A1 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.43 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis. Mohankumar K et al., 2020 Apr 1, Endocrinology
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  • Circular RNA hsa_circRNA_002178 silencing retards breast cancer progression via microRNA-328-3p-mediated inhibition of COL1A1. Liu T et al., 2020 Feb, J Cell Mol Med
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  • Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis. Besson B et al., 2020, PLoS One
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  • Conditional Deletion of Smad1 Ameliorates Glomerular Injury in Progressive Glomerulonephritis. Araki M et al., 2016 Aug 5, Sci Rep
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  • Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression. Chen HY et al., 2018, Cell Physiol Biochem
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  • Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction. Choong OK et al., 2019, Theranostics
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  • Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo. Chen HY et al., 2019 Apr 12, Antioxidants (Basel)
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  • No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction. Stroo I et al., 2018 Apr 2, BMC Nephrol
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  • Simulated physiological stretch increases expression of extracellular matrix proteins in human bladder smooth muscle cells via integrin alpha4/alphav-FAK-ERK1/2 signaling pathway. Chen S et al., 2017 Aug, World J Urol
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  • The Role of Cell Proliferation and Extracellular Matrix Accumulation Induced by Food Additive Butylated Hydroxytoluene in Uterine Leiomyoma. Chiang YF et al., 2021 Aug 31, Nutrients
    Read more