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Collagen III antibody [C2C3], C-term

GTX102997
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCOL3A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Collagen III antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1281
  • Target name
    COL3A1
  • Target description
    collagen type III alpha 1 chain
  • Target synonyms
    alpha1 (III) collagen; alpha-1 type III collagen; collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; EDS4A; EDSVASC; Ehlers-Danlos syndrome type IV, autosomal dominant; PMGEDSV
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02461
  • Protein Name
    Collagen alpha-1(III) chain
  • Scientific Description
    This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis.
    Read more
  • Modulation of Inherent Niches in 3D Multicellular MSC Spheroids Reconfigures Metabolism and Enhances Therapeutic Potential. Chen LC et al., 2021 Oct 14, Cells
    Read more
  • Cutaneous Regeneration Mechanism of beta-Sheet Silk Fibroin in a Rat Burn Wound Healing Model. Chou KC et al., 2021 Oct 14, Polymers (Basel)
    Read more
  • VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype. Mickle M et al., 2021 Jul, Mol Carcinog
    Read more
  • Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol Lett
    Read more
  • Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis. Chen QN et al., 2020 Apr 1, Exp Cell Res
    Read more
  • Huangqi Shengmai Yin Protects against Radiation-Induced Cardiac Fibrosis Injury by Regulating the TGF-beta1/Smads and MMPs. Gu J et al., 2019, Evid Based Complement Alternat Med
    Read more
  • Legumain Promotes Atherosclerotic Vascular Remodeling. Ozawa N et al., 2019 May 4, Int J Mol Sci
    Read more
  • Flavones hydroxylated at 5, 7, 3 and 4 ameliorate skin fibrosis via inhibiting activin receptor-like kinase 5 kinase activity. Zhang Y et al., 2019 Feb 11, Cell Death Dis
    Read more
  • The Implication of Substance P in the Development of Tendinopathy: A Case Control Study. Han SH et al., 2017 Jun 9, Int J Mol Sci
    Read more

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GeneTex anti collagen III antibody (GTX27778, 45 min RT) showed strong staining in FFPE sections of human skin(left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue between seminiferous tubules. The antibody showed strong extracellular staining within connective tissues across many organs with minimal background staining. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100oC - 20 minutes for antigen retrieval.
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