EP300 antibody [RW109]

GeneTex

EP300 antibody [RW109]

9

WB: 1:1000. ICC/IF: 1:100 - 1:200. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry

Research Use Only

Monoclonal

RW109

Unconjugated

EP300

EP300 lysine acetyltransferase

KAT3B, MKHK2, RSTS2, p300, histone acetyltransferase p300, E1A binding protein p300, E1A-associated protein p300, E1A-binding protein, 300kD, histone butyryltransferase p300, histone crotonyltransferase p300, p300 HAT, protein 2-hydroxyisobutyryltransferase p300, protein lactyltransferas p300, protein propionyltransferase p300

Mouse

IgG1

Histone acetyltransferase p300

Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.

-20°C or -80°C,2°C to 8°C

12352203