EpCAM antibody [ESA 214] (FITC)
GTX30708
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEPCAM
Overview
- SupplierGeneTex
- Product NameEpCAM antibody [ESA 214] (FITC)
- Delivery Days Customer9
- Application Supplier NoteIHC, ICC (frozen or formalin-fixed paraffin-embedded (FFPE) tissue sections, cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin~biotin system or polymer system, incubate 30 minutes at room temperature. IF, FITC~conjugated antibodies 10-20 microg/ml (1:10-1:20), incubate for 2 hours in the dark at RT or it can also be incubated overnight at 4C. FITC~conjugated antibodies, 0.2-1.0 microg/0.1 ml (1:200-1:1,000)
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDESA 214
- Concentration0.20 mg/ml
- ConjugateFITC
- Gene ID4072
- Target nameEPCAM
- Target descriptionepithelial cell adhesion molecule
- Target synonymsadenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1
- HostMouse
- IsotypeIgG1
- Protein IDP16422
- Protein NameEpithelial cell adhesion molecule
- Scientific DescriptionThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment.Read more
- A combinatorial panel for flow cytometry-based isolation of enteric nervous system cells from human intestine.Read more
- Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer.Read more
- Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer. Sacchetti A et al., 2021 May 26, ElifeRead more