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EpCAM antibody [ESA 214] (FITC)

GTX30708
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetEPCAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    EpCAM antibody [ESA 214] (FITC)
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC, ICC (frozen or formalin-fixed paraffin-embedded (FFPE) tissue sections, cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin~biotin system or polymer system, incubate 30 minutes at room temperature. IF, FITC~conjugated antibodies 10-20 microg/ml (1:10-1:20), incubate for 2 hours in the dark at RT or it can also be incubated overnight at 4C. FITC~conjugated antibodies, 0.2-1.0 microg/0.1 ml (1:200-1:1,000)
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ESA 214
  • Concentration
    0.20 mg/ml
  • Conjugate
    FITC
  • Gene ID4072
  • Target name
    EPCAM
  • Target description
    epithelial cell adhesion molecule
  • Target synonyms
    adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP16422
  • Protein Name
    Epithelial cell adhesion molecule
  • Scientific Description
    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment.
    Read more
  • A combinatorial panel for flow cytometry-based isolation of enteric nervous system cells from human intestine.
    Read more
  • Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer.
    Read more
  • Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer. Sacchetti A et al., 2021 May 26, Elife
    Read more