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FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-07 FOXP3 antibody [MF23] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-07 FOXP3 antibody [MF23] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-07 FOXP3 antibody [MF23] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)

FOXP3 antibody [MF23] (APC)

Research Use Only
GTX01488-07
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetFoxp3
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Overview

  • Supplier
    GeneTex
  • Product Name
    FOXP3 antibody [MF23] (APC)
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MF23
  • Concentration
    0.2 mg/ml
  • Conjugate
    APC (Allophycocyanin)
  • Formulation
    Liquid
  • Gene ID20371
  • Target name
    Foxp3
  • Target description
    forkhead box P3
  • Target synonyms
    forkhead box protein P3; JM2; scu; scurfin; scurfy; sf
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDQ99JB6
  • Protein Name
    Forkhead box protein P3
  • Scientific Description
    The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • CD25+ T cell depletion impairs murine squamous cell carcinoma development via modulation of antitumor immune responses. Ramos RN et al., 2012 Apr, Carcinogenesis
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  • Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells. Klein M et al., 2012 Feb 1, J Immunol
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  • Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. Ansari AA et al., 2011 Jan 15, J Immunol
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  • Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. Nagar M et al., 2008 Aug, Int Immunol
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  • Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2. Hombach AA et al., 2007 Dec 1, J Immunol
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  • Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Gavin MA et al., 2006 Apr 25, Proc Natl Acad Sci U S A
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