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FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)

FOXP3 antibody [MF23] (PE)

GTX01488-08
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetFoxp3
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Overview

  • Supplier
    GeneTex
  • Product Name
    FOXP3 antibody [MF23] (PE)
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MF23
  • Concentration
    0.2 mg/ml
  • Conjugate
    RPE
  • Gene ID20371
  • Target name
    Foxp3
  • Target description
    forkhead box P3
  • Target synonyms
    JM2, scurfin, sf, forkhead box protein P3, scurfy
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDQ99JB6
  • Protein Name
    Forkhead box protein P3
  • Scientific Description
    The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Ramos RN, Oliveira CE, Gasparoto TH, et al. CD25+ T cell depletion impairs murine squamous cell carcinoma development via modulation of antitumor immune responses. Carcinogenesis. 2012,33(4):902-9. doi: 10.1093/carcin/bgs103
    Read this paper
  • Klein M, Vaeth M, Scheel T, et al. Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells. J Immunol. 2012,188(3):1091-7. doi: 10.4049/jimmunol.1102045
    Read this paper
  • Ansari AA, Reimann KA, Mayne AE, et al. Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol. 2011,186(2):1044-59. doi: 10.4049/jimmunol.1003052
    Read this paper
  • Nagar M, Vernitsky H, Cohen Y, et al. Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. Int Immunol. 2008,20(8):1041-55. doi: 10.1093/intimm/dxn062
    Read this paper
  • Hombach AA, Kofler D, Hombach A, et al. Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2. J Immunol. 2007,179(11):7924-31.
    Read this paper
  • Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006,103(17):6659-64.
    Read this paper