![FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl) FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01488-08/GTX01488-08_20200428_FACS99_w_23053121_811.webp)
FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-08 FOXP3 antibody [MF23] (PE). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)
FOXP3 antibody [MF23] (PE)
GTX01488-08
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetFoxp3
Overview
- SupplierGeneTex
- Product NameFOXP3 antibody [MF23] (PE)
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMF23
- Concentration0.2 mg/ml
- ConjugateRPE
- Gene ID20371
- Target nameFoxp3
- Target descriptionforkhead box P3
- Target synonymsJM2, scurfin, sf, forkhead box protein P3, scurfy
- HostRat
- IsotypeIgG2b
- Protein IDQ99JB6
- Protein NameForkhead box protein P3
- Scientific DescriptionThe protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Ramos RN, Oliveira CE, Gasparoto TH, et al. CD25+ T cell depletion impairs murine squamous cell carcinoma development via modulation of antitumor immune responses. Carcinogenesis. 2012,33(4):902-9. doi: 10.1093/carcin/bgs103Read this paper
- Klein M, Vaeth M, Scheel T, et al. Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells. J Immunol. 2012,188(3):1091-7. doi: 10.4049/jimmunol.1102045Read this paper
- Ansari AA, Reimann KA, Mayne AE, et al. Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol. 2011,186(2):1044-59. doi: 10.4049/jimmunol.1003052Read this paper
- Nagar M, Vernitsky H, Cohen Y, et al. Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. Int Immunol. 2008,20(8):1041-55. doi: 10.1093/intimm/dxn062Read this paper
- Hombach AA, Kofler D, Hombach A, et al. Effective proliferation of human regulatory T cells requires a strong costimulatory CD28 signal that cannot be substituted by IL-2. J Immunol. 2007,179(11):7924-31.Read this paper
- Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006,103(17):6659-64.Read this paper


![FACS analysis of mouse C57Bl/6 splenocytes using GTX01488-07 FOXP3 antibody [MF23] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01488-07/GTX01488-07_20200428_FACS9_w_23053121_490.webp)
![FACS analysis of C57Bl/6 splenocytes stained FITC anti-mouse CD4 antibody, followed by intracellular staining with GTX80283-07 FOXP3 antibody [3G3] (APC). Right panel : Co-stained with FITC anti-mouse CD4 antibody and GTX80283-07 Left panel : Co-stained with FITC anti-mouse CD4 antibody and APC mouse IgG1 isotype control Antibody amount : 0.125 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX80283-07/GTX80283-07_20201020_FACS_11_w_23061322_251.webp)

![FACS analysis of C57Bl/6 splenocytes stained APC anti-mouse CD4 antibody, followed by intracellular staining with GTX80284 FOXP3 antibody [3G3] (PE). Right panel : Co-stained with APC anti-mouse CD4 antibody and GTX80284 Left panel : Co-stained with APC anti-mouse CD4 antibody and PE mouse IgG1 isotype control Antibody amount : 0.125 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX80284/GTX80284_20201020_FACS_64_w_23061322_985.webp)
