WB analysis of various samples using GTX81012 GLS antibody, C-term. Lane 1: human brain lysate Lane 2: human kidney lysate Lane 3: mouse brain lysate Loading : 20 microg per lane Dilution : 1:2000
WB analysis of various samples using GTX81012 GLS antibody, C-term. Lane 1: human brain lysate Lane 2: human kidney lysate Lane 3: mouse brain lysate Loading : 20 microg per lane Dilution : 1:2000
Glutaminase antibody, C-term
GTX81012
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGLS
Overview
- SupplierGeneTex
- Product NameGlutaminase antibody, C-term
- Delivery Days Customer7
- Application Supplier NoteWB: 1:1000. ICC/IF: 1:25. IHC-P: 1:25. FACS: 1:25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2744
- Target nameGLS
- Target descriptionglutaminase
- Target synonymsAAD20; CASGID; DEE71; EIEE71; GAC; GAM; GDPAG; GLS1; glutaminase C; glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; KGA; K-glutaminase; L-glutamine amidohydrolase
- HostRabbit
- IsotypeIgG
- Protein IDO94925
- Protein NameGlutaminase kidney isoform, mitochondrial
- Scientific DescriptionThis gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade.Read more
- DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus. Potier B et al., 2022 Jan 6, Int J Mol SciRead more
- Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer. Bruntz RC et al., 2019 Jul 12, ProteomicsRead more
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism. Johnson MO et al., 2018 Dec 13, CellRead more
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. Xiang Y et al., 2015 Jun, J Clin InvestRead more