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IHC-P analysis of human brain tissue using GTX81012 GLS antibody, C-term. Antigen retrieval : heat-induced antigen retrieval with a citrate buffer (pH6) Dilution : 1:25
IHC-P analysis of human brain tissue using GTX81012 GLS antibody, C-term. Antigen retrieval : heat-induced antigen retrieval with a citrate buffer (pH6) Dilution : 1:25
IHC-P analysis of human brain tissue using GTX81012 GLS antibody, C-term. Antigen retrieval : heat-induced antigen retrieval with a citrate buffer (pH6) Dilution : 1:25

Glutaminase antibody, C-term

GTX81012
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGLS
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Overview

  • Supplier
    GeneTex
  • Product Name
    Glutaminase antibody, C-term
  • Delivery Days Customer
    7
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:25. IHC-P: 1:25. FCM: 1:25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2744
  • Target name
    GLS
  • Target description
    glutaminase
  • Target synonyms
    AAD20, CASGID, DEE71, EIEE71, GAC, GAM, GDPAG, GLS1, KGA, glutaminase kidney isoform, mitochondrial, K-glutaminase, L-glutamine amidohydrolase, glutaminase C, glutaminase, phosphate-activated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO94925
  • Protein Name
    Glutaminase kidney isoform, mitochondrial
  • Scientific Description
    This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade.
    Read this paper
  • DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus. Potier B et al., 2022 Jan 6, Int J Mol Sci
    Read this paper
  • Inhibition of Anaplerotic Glutaminolysis Underlies Selenite Toxicity in Human Lung Cancer. Bruntz RC et al., 2019 Jul 12, Proteomics
    Read this paper
  • Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism. Johnson MO et al., 2018 Dec 13, Cell
    Read this paper
  • Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. Xiang Y et al., 2015 Jun, J Clin Invest
    Read this paper

Datasheet

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