HIF1 alpha antibody [GT10211]
GTX628480
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetHIF1A
Overview
- SupplierGeneTex
- Product NameHIF1 alpha antibody [GT10211]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:100-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT10211
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3091
- Target nameHIF1A
- Target descriptionhypoxia inducible factor 1 subunit alpha
- Target synonymsHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78, hypoxia-inducible factor 1-alpha, ARNT interacting protein, PAS domain-containing protein 8, basic-helix-loop-helix-PAS protein MOP1, class E basic helix-loop-helix protein 78, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1
- HostMouse
- IsotypeIgG2a
- Protein IDQ16665
- Protein NameHypoxia-inducible factor 1-alpha
- Scientific DescriptionHypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Keitoku M, Yonemitsu I, Ikeda Y, et al. Differential Recovery Patterns of the Maxilla and Mandible after Eliminating Nasal Obstruction in Growing Rats. J Clin Med. 2022,11(24). doi: 10.3390/jcm11247359Read this paper
- Chang YL, Chang SD, Chao AS, et al. Effect of Hypoxia on Glucose Transporter 1 and 3 Gene Expression in Placental Mesenchymal Stem Cells Derived from Growth-Restricted Fetuses. Genes (Basel). 2022,13(5). doi: 10.3390/genes13050752Read this paper
- Beak JY, Kang HS, Huang W, et al. The nuclear receptor RORα preserves cardiomyocyte mitochondrial function by regulating caveolin-3-mediated mitophagy. J Biol Chem. 2021,297(6):101358. doi: 10.1016/j.jbc.2021.101358Read this paper
- Zhang C, Chen M, Tao Q, et al. Cobalt chloride-stimulated hypoxia promotes the proliferation of cholesteatoma keratinocytes via the PI3K/Akt signaling pathway. Int J Med Sci. 2021,18(15):3403-3411. doi: 10.7150/ijms.60617Read this paper
- Sharma S, Wang J, Alqassim E, et al. Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells. Genome Biol. 2019,20(1):37. doi: 10.1186/s13059-019-1651-1Read this paper
- Masola V, Bellin G, Vischini G, et al. Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury. Oncotarget. 2018,9(90):36185-36201. doi: 10.18632/oncotarget.26324Read this paper
- Matsumura-Matsuda E, Sekiya M, Omoto-Inuzuka M, et al. A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges. Intern Med. 2018,57(7):979-985. doi: 10.2169/internalmedicine.9242-17Read this paper
- Saki M, Makino H, Javvadi P, et al. EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair. Mol Cancer Res. 2017,15(11):1503-1516. doi: 10.1158/1541-7786.MCR-17-0136Read this paper
- Shih JW, Chiang WF, Wu ATH, et al. Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression. Nat Commun. 2017,8:15874. doi: 10.1038/ncomms15874Read this paper
- Sharma S, Wang J, Cortes Gomez E, et al. Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes. Hum Mol Genet. 2017,26(7):1328-1339. doi: 10.1093/hmg/ddx041Read this paper
Datasheet
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