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IHC-P analysis of human kidney tissue using GTX30115 HIF1 alpha antibody [H1alpha67].
IHC-P analysis of human kidney tissue using GTX30115 HIF1 alpha antibody [H1alpha67].
IHC-P analysis of human kidney tissue using GTX30115 HIF1 alpha antibody [H1alpha67].

HIF1 alpha antibody [H1alpha67]

GTX30115
GeneTex
ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Bovine, Canine, Ferret, Human, Monkey, Mouse, Porcine, Primate, Rat, Sheep
TargetHIF1A
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Overview

  • Supplier
    GeneTex
  • Product Name
    HIF1 alpha antibody [H1alpha67]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. ICC/IF: 1:10 - 1:500. IHC-P: 1:100 - 1:300. FCM: 1:10 - 1:1000. IP: 1:10. ELISA: 1:100 - 1:2000. ChIP assay: 1:10 - 1:500. Gel supershift assays: 1:1 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Gel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    H1alpha67
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3091
  • Target name
    HIF1A
  • Target description
    hypoxia inducible factor 1 subunit alpha
  • Target synonyms
    HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78, hypoxia-inducible factor 1-alpha, ARNT interacting protein, PAS domain-containing protein 8, basic-helix-loop-helix-PAS protein MOP1, class E basic helix-loop-helix protein 78, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ16665
  • Protein Name
    Hypoxia-inducible factor 1-alpha
  • Scientific Description
    Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
  • Reactivity
    Avian, Bovine, Canine, Ferret, Human, Monkey, Mouse, Porcine, Primate, Rat, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth.
    Read this paper
  • Hypoxia-induced abrogation of contact-dependent inhibition of rheumatoid arthritis synovial fibroblast proliferation. Nonomura Y et al., 2009 Apr, J Rheumatol
    Read this paper
  • Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Catrina SB et al., 2006 Aug 1, Clin Cancer Res
    Read this paper