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HNF1 alpha antibody [N1N3]

GTX113850
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetHNF1A
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Overview

  • Supplier
    GeneTex
  • Product Name
    HNF1 alpha antibody [N1N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.27 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6927
  • Target name
    HNF1A
  • Target description
    HNF1 homeobox A
  • Target synonyms
    HNF-1-alpha, HNF-1A, HNF1, HNF1alpha, HNF4A, IDDM20, LFB1, MODY3, TCF-1, TCF1, hepatocyte nuclear factor 1-alpha, albumin proximal factor, hepatic nuclear factor 1, interferon production regulator factor, liver-specific transcription factor LF-B1, transcription factor 1, hepatic
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP20823
  • Protein Name
    Hepatocyte nuclear factor 1-alpha
  • Scientific Description
    The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5-GTTAATNATTAAC-3. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Onuma S, Manabe A, Yoshino Y, et al. Upregulation of Chemoresistance by Mg(2+) Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells. Cells. 2021,10(5). doi: 10.3390/cells10051179
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  • Lammi C, Aiello G, Bollati C, et al. Trans-Epithelial Transport, Metabolism, and Biological Activity Assessment of the Multi-Target Lupin Peptide LILPKHSDAD (P5) and Its Metabolite LPKHSDAD (P5-Met). Nutrients. 2021,13(3). doi: 10.3390/nu13030863
    Read this paper
  • Maruhashi R, Akizuki R, Sato T, et al. Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models. Biochim Biophys Acta Mol Cell Res. 2018,1865(3):470-479. doi: 10.1016/j.bbamcr.2017.12.005
    Read this paper
  • Kowalczyk AE, Krazinski BE, Godlewski J, et al. SATB1 is Down-regulated in Clear Cell Renal Cell Carcinoma and Correlates with miR-21-5p Overexpression and Poor Prognosis. Cancer Genomics Proteomics. 2016,13(3):209-17.
    Read this paper
  • Yasui K, Tanabe H, Miyoshi N, et al. Effects of (-)-epigallocatechin-3-O-gallate on expression of gluconeogenesis-related genes in the mouse duodenum. Biomed Res. 2011,32(5):313-20.
    Read this paper
  • Yasui K, Miyoshi N, Tababe H, et al. Effects of oolong tea on gene expression of gluconeogenic enzymes in the mouse liver and in rat hepatoma H4IIE cells. J Med Food. 2011,14(9):930-8. doi: 10.1089/jmf.2010.1396
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