ICC/IF analysis of HeLa cells using GTX25832 hnRNP A1 antibody [9H10] at 10 microg/mL. Cells were fixed and permeabilized with cold methanol followed by cold methanol:acetone.
![WB analysis of (1)HEK-293T (2) HeLa (3) G361 (4) COS7 (5) MDBK (6) NRK (7) CHO cells using GTX25832 hnRNP A1 antibody [9H10] at 1 microg/mL.](https://www.genetex.com/upload/website/prouct_img/normal/GTX25832/GTX25832_20170605_WB_w_23060722_517.webp "WB analysis of (1)HEK-293T (2) HeLa (3) G361 (4) COS7 (5) MDBK (6) NRK (7) CHO cells using GTX25832 hnRNP A1 antibody [9H10] at 1 microg/mL.")
ICC/IF analysis of HeLa cells using GTX25832 hnRNP A1 antibody [9H10] at 10 microg/mL. Cells were fixed and permeabilized with cold methanol followed by cold methanol:acetone.
hnRNP A1 antibody [9H10]
GTX25832
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Canine, Hamster, Human, Monkey, Mouse, Rat
TargetHNRNPA1
Overview
- SupplierGeneTex
- Product NamehnRNP A1 antibody [9H10]
- Delivery Days Customer9
- Application Supplier NoteWB: 0.5-1.0 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9H10
- ConjugateUnconjugated
- Gene ID3178
- Target nameHNRNPA1
- Target descriptionheterogeneous nuclear ribonucleoprotein A1
- Target synonymsALS19; ALS20; epididymis secretory sperm binding protein; helix-destabilizing protein; heterogeneous nuclear ribonucleoprotein A1; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP core protein A1-like 3; hnRNP-A1; HNRPA1; HNRPA1L3; IBMPFD3; nuclear ribonucleoprotein particle A1 protein; putative heterogeneous nuclear ribonucleoprotein A1-like 3; single-strand DNA-binding protein UP1; single-strand RNA-binding protein; UP 1
- HostMouse
- IsotypeIgG2b
- Protein IDP09651
- Protein NameHeterogeneous nuclear ribonucleoprotein A1
- Scientific DescriptionThe hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variant have multiple alternative transcription initiation sites and multiple polyA sites.
- ReactivityBovine, Canine, Hamster, Human, Monkey, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203