Bio-Connect

hnRNP A1 antibody [9H10]

GTX80389
GeneTex
TargetHNRNPA1
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    hnRNP A1 antibody [9H10]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Human hnRNP-A1. Detects a band of approximately 34 kDa
  • Application Supplier Note
    Recommended Starting Dilutions:For WB: Use at 1:2000-1:4000Optimal dilutions should be determined experimentally by the researcher.
  • Clone ID
    9H10
  • Formulation
    Liquid
  • Gene ID3178
  • Target name
    HNRNPA1
  • Target description
    heterogeneous nuclear ribonucleoprotein A1
  • Target synonyms
    ALS19; ALS20; epididymis secretory sperm binding protein; helix-destabilizing protein; heterogeneous nuclear ribonucleoprotein A1; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP core protein A1-like 3; hnRNP-A1; HNRPA1; HNRPA1L3; IBMPFD3; nuclear ribonucleoprotein particle A1 protein; putative heterogeneous nuclear ribonucleoprotein A1-like 3; single-strand DNA-binding protein UP1; single-strand RNA-binding protein; UP 1
  • Protein IDP09651
  • Protein Name
    Heterogeneous nuclear ribonucleoprotein A1
  • Scientific Description
    This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion. Sareen D et al., 2013 Oct 23, Sci Transl Med
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  • Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43. Fuentealba RA et al., 2010 Aug 20, J Biol Chem
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