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ProductsBack/Isorhamnetin [480-19-3]
Chemical Structure
Chemical Structure
Chemical Structure

Isorhamnetin [480-19-3]

Research Use Only
CDX-I0174
Chemodex
CAS Number480-19-3
DownloadDatasheet
Product group Chemicals
Estimated Purity>98%
Molecular Weight316.26
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Overview

  • Supplier
    Chemodex
  • Product Name
    Isorhamnetin [480-19-3]
  • Delivery Days Customer
    10
  • CAS Number
    480-19-3
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C16H12O7
  • Molecular Weight
    316.26
  • Scientific Description
    Chemical. CAS: 480-19-3. Formula: C16H12O7. MW: 316.26. Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin. It shows diverse biological activities, including antioxidant, cardioprotective, anti-inflammatory, neuroprotective, antiobesity, antiviral, antituberculosis and anticancer properties. Isorhamnetin exerts anticancer activity, through induction of apoptosis and inhibition of cell proliferation and invasion. It suppresses colon cancer cell growth through the PI3K-Akt-mTOR pathway. It inhibits the NF-kappaB signaling pathway. Isorhamnetin selectively inhibited NLRP3 and AIM2 inflammasome activation and down-regulated expression of pro-inflammatory cytokines. It has powerful antioxidant action through its ability to scavenge free radicals and inhibits xanthine oxidase. Isorhamnetin is a PPARgamma antagonist and inhibits adipogenesis, with beneficial effect on the prevention and treatment of obesity. - Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin. It shows diverse biological activities, including antioxidant, cardioprotective, anti-inflammatory, neuroprotective, antiobesity, antiviral, antituberculosis and anticancer properties. Isorhamnetin exerts anticancer activity, through induction of apoptosis and inhibition of cell proliferation and invasion. It suppresses colon cancer cell growth through the PI3K-Akt-mTOR pathway. It inhibits the NF-kappaB signaling pathway. Isorhamnetin selectively inhibited NLRP3 and AIM2 inflammasome activation and down-regulated expression of pro-inflammatory cytokines. It has powerful antioxidant action through its ability to scavenge free radicals and inhibits xanthine oxidase. Isorhamnetin is a PPARgamma antagonist and inhibits adipogenesis, with beneficial effect on the prevention and treatment of obesity.
  • SMILES
    O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(OC)=C3)=C1O
  • Storage Instruction
    2°C to 8°C,RT
  • UNSPSC
    12352200