Lamin B2 antibody [GT144]
GTX628803
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetLMNB2
Overview
- SupplierGeneTex
- Product NameLamin B2 antibody [GT144]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT144
- Concentration0.81 mg/ml
- ConjugateUnconjugated
- Gene ID84823
- Target nameLMNB2
- Target descriptionlamin B2
- Target synonymsepididymis secretory sperm binding protein; EPM9; LAMB2; lamin B3; lamin-B2; LMN2; MCPH27
- HostMouse
- IsotypeIgG2a
- Protein IDQ03252
- Protein NameLamin-B2
- Scientific DescriptionThe nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Excessive reactive oxygen species induce transcription-dependent replication stress.Read more
- Differentiation-dependent changes in lamin B1 dynamics and lamin B receptor localization.Read more
- The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity. Jevtic P et al., 2019 Jun, EMBO RepRead more
- Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression. Yang SL et al., 2017 Dec 1, OncotargetRead more
- RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. Urban V et al., 2016 Aug 15, J Cell BiolRead more