ME1 antibody

Name: ME1 antibody
SKU: GTX104122_G10
Availability: BackOrder

GTX104122

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetME1

Overview

Supplier
GeneTex
Product Name
ME1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.68 mg/ml
Conjugate
Unconjugated
Gene ID4199
Target name
ME1
Target description
malic enzyme 1
Target synonyms
HUMNDME, MES, NADP-dependent malic enzyme, Malic enzyme, cytoplasmic, NADP-ME, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), malic enzyme 1, NADP(+)-dependent, cytosolic, malic enzyme 1, soluble, pyruvic-malic carboxylase
Host
Rabbit
Isotype
IgG
Protein IDP48163
Protein Name
NADP-dependent malic enzyme
Scientific Description
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Igelmann S, Lessard F, Uchenunu O, et al. A hydride transfer complex reprograms NAD metabolism and bypasses senescence. Mol Cell. 2021,81(18):3848-3865.e19. doi: 10.1016/j.molcel.2021.08.028
Read this paper
Tsai YT, Ruan JW, Chang CS, et al. Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Nutrients. 2020,12(3). doi: 10.3390/nu12030726
Read this paper
Choi EJ, Jung BJ, Lee SH, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017,36(37):5285-5295. doi: 10.1038/onc.2017.153
Read this paper