mGluR5 antibody

GeneTex

mGluR5 antibody

9

WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

GRM5

glutamate metabotropic receptor 5

glutamate receptor, metabotropic 5; GPRC1E; metabotropic glutamate receptor 5; mGlu5; MGLUR5; PPP1R86; protein phosphatase 1, regulatory subunit 86

Rabbit

IgG

Metabotropic glutamate receptor 5

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors (GPCRs) that contain 7 membrane-spanning domains and a large extracellular N-terminal region. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1-alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).

-20°C or -80°C,2°C to 8°C

12352203