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ProductsBack/MST1 (phospho Thr183) + MST2 (phospho Thr180) antibody

MST1 (phospho Thr183) + MST2 (phospho Thr180) antibody

GTX133948
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
TargetSTK4
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Overview

  • Supplier
    GeneTex
  • Product Name
    MST1 (phospho Thr183) + MST2 (phospho Thr180) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.54 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6789
  • Target name
    STK4
  • Target description
    serine/threonine kinase 4
  • Target synonyms
    hippo homolog; kinase responsive to stress 2; KRS2; mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; serine/threonine-protein kinase 4; serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; YSK3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13043
  • Protein Name
    Serine/threonine-protein kinase 4
  • Scientific Description
    The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and its possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cryo-EM structure of the Hippo signaling integrator human STRIPAK. Jeong BC et al., 2021 Mar, Nat Struct Mol Biol
    Read more
  • STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. Bae SJ et al., 2020 Apr 15, Elife
    Read more

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