MST1 (phospho Thr183) + MST2 (phospho Thr180) antibody
GTX133948
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetSTK4
Overview
- SupplierGeneTex
- Product NameMST1 (phospho Thr183) + MST2 (phospho Thr180) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.54 mg/ml
- ConjugateUnconjugated
- Gene ID6789
- Target nameSTK4
- Target descriptionserine/threonine kinase 4
- Target synonymsKRS2, MST1, YSK3, serine/threonine-protein kinase 4, STE20-like kinase MST1, hippo homolog, kinase responsive to stress 2, mammalian STE20-like protein kinase 1, mammalian sterile 20-like 1, serine/threonine-protein kinase Krs-2
- HostRabbit
- IsotypeIgG
- Protein IDQ13043
- Protein NameSerine/threonine-protein kinase 4
- Scientific DescriptionThe protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and its possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Jeong BC, Bae SJ, Ni L, et al. Cryo-EM structure of the Hippo signaling integrator human STRIPAK. Nat Struct Mol Biol. 2021,28(3):290-299. doi: 10.1038/s41594-021-00564-yRead this paper
- Bae SJ, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. Elife. 2020,9. doi: 10.7554/eLife.54863Read this paper






