WB analysis of human bone marrow lysate using GTX89215 MUTYH antibody, C-term. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human bone marrow lysate using GTX89215 MUTYH antibody, C-term. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
MUTYH antibody, C-term
GTX89215
Overview
- SupplierGeneTex
- Product NameMUTYH antibody, C-term
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to recognise all reported isoforms (NP_036354.1; NP_001041636.1; NP_001041637.1; NP_001041638.1; NP_001121897.1).
- Application Supplier NoteWB: 0.1-0.3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID4595
- Target nameMUTYH
- Target descriptionmutY DNA glycosylase
- Target synonymsA/G-specific adenine DNA glycosylase; adenine DNA glycosylase; mutY homolog; mutY-like protein; MYH
- HostGoat
- IsotypeIgG
- Protein IDQ9UIF7
- Protein NameAdenine DNA glycosylase
- Scientific DescriptionThis gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203