IHC-P analysis of human breast carcinoma tissue using GTX66680 MUTYH antibody. Dilution : 1:50
IHC-P analysis of human breast carcinoma tissue using GTX66680 MUTYH antibody. Dilution : 1:50
MUTYH antibody
GTX66680
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMUTYH
Overview
- SupplierGeneTex
- Product NameMUTYH antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4595
- Target nameMUTYH
- Target descriptionmutY DNA glycosylase
- Target synonymsA/G-specific adenine DNA glycosylase; adenine DNA glycosylase; mutY homolog; mutY-like protein; MYH
- HostRabbit
- IsotypeIgG
- Protein IDQ9UIF7
- Protein NameAdenine DNA glycosylase
- Scientific DescriptionThis gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203