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ProductsBack/NDP52 antibody

NDP52 antibody

Research Use Only
GTX115378
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCALCOCO2
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Overview

  • Supplier
    GeneTex
  • Product Name
    NDP52 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.57 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID10241
  • Target name
    CALCOCO2
  • Target description
    calcium binding and coiled-coil domain 2
  • Target synonyms
    antigen nuclear dot 52 kDa protein; calcium-binding and coiled-coil domain-containing protein 2; NDP52; nuclear domain 10 protein 52; nuclear domain 10 protein NDP52; nuclear dot protein 52
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13137
  • Protein Name
    Calcium-binding and coiled-coil domain-containing protein 2
  • Scientific Description
    The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Baicalein Activates Parkin-Dependent Mitophagy through NDP52 and OPTN. Ke PY et al., 2022 Mar 28, Cells
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  • Recruitment of LC3 by Campylobacter jejuni to Bacterial Invasion Site on Host Cells via the Rac1-Mediated Signaling Pathway. Fukushima S et al., 2022, Front Cell Infect Microbiol
    Read more
  • Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity. Hall BS et al., 2022 Apr, Autophagy
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  • AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Hung CM et al., 2021 Apr, Sci Adv
    Read more
  • Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells. Robichaud S et al., 2021 Nov, Autophagy
    Read more
  • Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis. Wang X et al., 2020 Jul, Biomed Pharmacother
    Read more
  • Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization. Ogawa M et al., 2020 Jan 13, Commun Biol
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  • Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform. Zachari M et al., 2019 Sep 9, Dev Cell
    Read more
  • Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P. Liao CC et al., 2018, Autophagy
    Read more
  • Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer. Chen CH et al., 2018 Mar 1, Clin Cancer Res
    Read more