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Nestin antibody [GT623]

Name: Nestin antibody [GT623]
SKU: GTX630201_G10
Availability: BackOrder

GTX630201

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman

TargetNES

Overview

Supplier
GeneTex
Product Name
Nestin antibody [GT623]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
GT623
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID10763
Target name
NES
Target description
nestin
Target synonyms
Nbla00170, nestin
Host
Mouse
Isotype
IgG1
Protein IDP48681
Protein Name
Nestin
Scientific Description
Nestin is an intermediate filament protein that was first identified with a monoclonal antibody by Hockfield and McKay (1985) [PubMed 4078630]. It is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments.[supplied by OMIM]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Seo Y, Han S, Song BW, et al. Endogenous Neural Stem Cell Activation after Low-Intensity Focused Ultrasound-Induced Blood-Brain Barrier Modulation. Int J Mol Sci. 2023,24(6). doi: 10.3390/ijms24065712
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Yao P, Yu Q, Zhu L, et al. Wnt/PCP pathway regulates the migration and neural differentiation of mesenchymal stem cells in vitro. Folia Histochem Cytobiol. 2022,60(1):44-54. doi: 10.5603/FHC.a2022.0006
Read this paper
Ma L, Ye Z, Zhang Y, et al. Irradiated microvascular endothelial cells may induce bystander effects in neural stem cells leading to neurogenesis inhibition. J Radiat Res. 2022,63(2):192-201. doi: 10.1093/jrr/rrab125
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Zhang M, Wang J, Zhang K, et al. Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain. Nat Commun. 2021,12(1):5091. doi: 10.1038/s41467-021-25353-5
Read this paper
Deng H, Yang F, Ma X, et al. Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM Mice. Cell Transplant. 2020,29:963689720927392. doi: 10.1177/0963689720927392
Read this paper
Mansel C, Fross S, Rose J, et al. Lead exposure reduces survival, neuronal determination, and differentiation of P19 stem cells. Neurotoxicol Teratol. 2019,72:58-70. doi: 10.1016/j.ntt.2019.01.005
Read this paper
Koffler J, Zhu W, Qu X, et al. Biomimetic 3D-printed scaffolds for spinal cord injury repair. Nat Med. 2019,25(2):263-269. doi: 10.1038/s41591-018-0296-z
Read this paper
Liu H, He Z, April SL, et al. Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell Death Differ. 2019,26(6):1048-1061. doi: 10.1038/s41418-018-0182-8
Read this paper
Xie MQ, Chen ZC, Zhang P, et al. Newborn dopaminergic neurons are associated with the migration and differentiation of SVZ-derived neural progenitors in a 6-hydroxydopamin-injected mouse model. Neuroscience. 2017,352:64-78. doi: 10.1016/j.neuroscience.2017.03.045
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Aguilera-Castrejon A, Pasantes-Morales H, Montesinos JJ, et al. Improved Proliferative Capacity of NP-Like Cells Derived from Human Mesenchymal Stromal Cells and Neuronal Transdifferentiation by Small Molecules. Neurochem Res. 2017,42(2):415-427. doi: 10.1007/s11064-016-2086-7
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Nestin antibody [GT623]

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