IHC (Free Floating) analysis of PFA-fixed rat hippocampus tissue using GTX00837 NeuN antibody. The NeuN antibody stains the nuclei and distal perikarya of most neurons, while the IBA1 antibody specifically labels microglial cells. Red : Primary antibody Green : IBA1 Dilution : 1:5,000
NeuN antibody
GTX00837
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRBFOX3
Overview
- SupplierGeneTex
- Product NameNeuN antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID146713
- Target nameRBFOX3
- Target descriptionRNA binding fox-1 homolog 3
- Target synonymsfox-1 homolog C; FOX3; FOX-3; hexaribonucleotide binding protein 3; HRNBP3; NEUN; neuN antigen; neuronal nuclei antigen; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog 3
- HostChicken
- IsotypeIgY
- Scientific DescriptionThis gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury. Mu X et al., 2021 Nov 12, Sci AdvRead more
- Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions. Liu H et al., 2021 Jan 7, Nat CommunRead more