
Western blot of rat brain homogenates stained with GTX16208. Antibody binds closely spaced 48 and 46kDa bands.
NeuN antibody
GTX16208
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine, Chicken, Equine, Human, Mouse, Porcine, Rat
TargetRBFOX3
Overview
- SupplierGeneTex
- Product NameNeuN antibody
- Delivery Days Customer9
- Application Supplier NoteWB:1:5,000-1:10,000. IF/IHC 1:500-1:1,000.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID146713
- Target nameRBFOX3
- Target descriptionRNA binding fox-1 homolog 3
- Target synonymsFOX-3, FOX3, HRNBP3, NEUN, RNA binding protein fox-1 homolog 3, RNA binding protein, fox-1 homolog 3, fox-1 homolog C, hexaribonucleotide binding protein 3, neuN antigen, neuronal nuclei antigen
- HostRabbit
- IsotypeIgG
- Protein IDA6NFN3
- Protein NameRNA binding protein fox-1 homolog 3
- Scientific DescriptionThis gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
- ReactivityBovine, Chicken, Equine, Human, Mouse, Porcine, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases.Read this paper
- Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response. Manet C et al., 2022 Dec 20, J NeuroinflammationRead this paper
- Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene. Chao J et al., 2022 Jun 17, iScienceRead this paper








![NeuN antibody detects NeuN protein at nucleus by immunofluorescent analysis. Sample: DIV9 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: NeuN stained by NeuN antibody (GTX132974) diluted at 1:250. Red: Tau, an axon marker, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX132974/GTX132974_44986_20230519_ICC_IF_R_23053001_624.webp)


![NeuN antibody [HL2194] detects NeuN protein by immunohistochemical analysis. Sample: Paraffin-embedded rat tissues. NeuN stained by NeuN antibody [HL2194] (GTX638198) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX638198/GTX638198_T-44942_20230424_IHC-P_multiple_R_23050918_845.webp)
