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Paraformaldehyde fixed frozen section of adult rat cortex stained with GTX16208 in red and counterstained for DNA in blue. Note that GTX16208 stains neuronal nuclei and distal perikarya. These antibodies do not bind to the nuclei of perikarya of non-neuronal cells, so that they can be used to identify neurons.
Paraformaldehyde fixed frozen section of adult rat cortex stained with GTX16208 in red and counterstained for DNA in blue. Note that GTX16208 stains neuronal nuclei and distal perikarya. These antibodies do not bind to the nuclei of perikarya of non-neuronal cells, so that they can be used to identify neurons.
Paraformaldehyde fixed frozen section of adult rat cortex stained with GTX16208 in red and counterstained for DNA in blue. Note that GTX16208 stains neuronal nuclei and distal perikarya. These antibodies do not bind to the nuclei of perikarya of non-neuronal cells, so that they can be used to identify neurons.

NeuN antibody

GTX16208
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetRBFOX3
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Overview

  • Supplier
    GeneTex
  • Product Name
    NeuN antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB:1:5,000-1:10,000. IF/IHC 1:500-1:1,000.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID146713
  • Target name
    RBFOX3
  • Target description
    RNA binding fox-1 homolog 3
  • Target synonyms
    FOX-3, FOX3, HRNBP3, NEUN, RNA binding protein fox-1 homolog 3, RNA binding protein, fox-1 homolog 3, fox-1 homolog C, hexaribonucleotide binding protein 3, neuN antigen, neuronal nuclei antigen
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDA6NFN3
  • Protein Name
    RNA binding protein fox-1 homolog 3
  • Scientific Description
    This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases.
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  • Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response. Manet C et al., 2022 Dec 20, J Neuroinflammation
    Read more
  • Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene. Chao J et al., 2022 Jun 17, iScience
    Read more