Cell lysates of Ramos (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human NFATc1 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Cell lysates of Ramos (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human NFATc1 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
NFAT2 antibody [AT1C3]
GTX50030
Overview
- SupplierGeneTex
- Product NameNFAT2 antibody [AT1C3]
- Delivery Days Customer9
- Application Supplier NoteWe recommend the following starting dilutions:Western Blot: Use at 1:1000 ~ 2000.Optimal working concentrations should be determined experimentally by the end user.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAT1C3
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4772
- Target nameNFATC1
- Target descriptionnuclear factor of activated T cells 1
- Target synonymsNFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NF-ATc1.2; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- HostMouse
- IsotypeIgG2a
- Protein IDO95644
- Protein NameNuclear factor of activated T-cells, cytoplasmic 1
- Scientific DescriptionThe product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells. Seite JF et al., 2014 Jan, J Allergy Clin ImmunolRead more